oral biology researchers working with fluids

About Research and Discovery

Our programs in basic sciences, clinical sciences, social and behavioral sciences and public health help bring current research into our classrooms, clinics and dental practices statewide. Five research clusters investigate everything from neuroscience to oral health disparities.

Awards, Funding & Submitted Proposals

$8,639,015

Total Awards

Fiscal Year 2025

79
Proposals Submitted
43
Awards Granted
32
New Proposals Submitted
Dr. Artinger at a microscope

Research at a glance 2025

129
Publications by faculty
29
Faculty collaborations
2
Resident and graduate student grants
Oral Health Clinical Research Center takes a photo
Oral Health Clinical Research Center

The mission of the Oral Health Clinical Research Center (OHCRC) is to enhance oral health by transferring basic and applied research knowledge and new technical advances into patient-oriented research. The OHCRC helps researchers in all phases of a project.

a researcher types in code to operate the chewing robot lab tech
Minnesota Dental Research Center for Biomaterials and Biomechanics

The Minnesota Dental Research Center for Biomaterials and Biomechanics (MDRCBB) is a multi-disciplinary resource dedicated to furthering research and development in biomaterials, biomechanics, and nano-technology.

Dr. Louis Mansky in the Institute for Molecular Virology
Institute for Molecular Virology

The Institute for Molecular Virology breaks down the barriers that exist in traditional academic ‘siloes’ to foster collegial interactions that result in new scientific collaborations and in the advancement of prevention, diagnosis, and treatment of viral disease.

Publications

two reseachers in the Costalonga Lab working with fluids and pipets

With hundreds of published papers ranging on topics from microbiology, treating pediatric patients, addressing obstacles in access to care, and developing better technology for the purpose of oral health, School of Dentistry researchers and faculty lead the way toward the future of oral health care.

Prior years' publication lists are available upon request. Please contact [email protected] for additional information.

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Administration

Bachour PC, Klabunde RT, Grünheid T. 2025. Usefulness of an artificial intelligence-assisted indirect bonding method for optimizing orthodontic bracket positioning. Angle Orthodontist. 96(1):93-99. DOI: 10.2319/022425-157.1

Dargis R, Pajak J, Ariyawansa P, Morais MC, Jardine PJ, Arya G. 2025. Regulation of the ordinal DNA translocation cycle in bacteriophage Φ29 through trans-subunit interactions. Proceedings of the National Academy of Sciences of the United States of America. 122(27):Article e2504780122. DOI: 10.1073/pnas.2504780122

Mays K, Lee A, Forester R, Brear S. 2025. The American Dental Education Association 2022 Climate Study Recommendations and Strategic Actions. Journal of dental education. 89(5):798-804. DOI: 10.1002/jdd.13833

Mays KA, Ouyang I, Cooper A, Wang Q. 2025. Finances and employment domains are strong determinants when screening for unmet social needs in a predoctoral dental clinic: A preliminary assessment. Journal of dental education. 89(4):476-484. DOI: 10.1002/jdd.13776

Nirkhiwale A, Tartar W, Mays KA. 2025. An Analysis of Student's Perspective of an Early Team-Based Denture Clinical Experience. Journal of dental education. 89(11):1593-1600. DOI: 10.1002/jdd.13883

Woodson M, Prokhorov NS, Scott SD, Zhao W, Zhang W, Choi KH, Jardine PJ, Morais MC. 2025. Phi29 assembly intermediates reveal how scaffold interactions with capsid protein drive capsid construction and maturation. Science Advances. 11(12):Article eadk8779. DOI: 10.1126/sciadv.adk8779

Developmental and Surgical Sciences

Al-Obaidi S, Papageorgiou SN, Saade M, Caradonna KM, Kantarci A, Will L, Motro M. 2025. Influence of genetic and environmental factors on transverse growth. European Journal of Orthodontics. 47(2):Article cjaf003. DOI: 10.1093/ejo/cjaf003

Asinas ED, Clark R, Nelson J, Llorens JEA, Mansky K, Tasca A. 2025. Mandibular-Derived Monocytes from 1-Year-Old Mice Have Enhanced Osteoclast Differentiation and Differentially Regulated Gene Expression Compared to Femur-Derived Monocytes. Biology. 14(3):Article 273. DOI: 10.3390/biology14030273

Astleford-Hopper K, Abrahante Llorens JE, Bradley EW, Mansky KC. 2025. Lysine specific demethylase 1 conditional myeloid cell knockout mice have decreased osteoclast differentiation due to increased IFN-β gene expression. JBMR Plus. 9(1):Article ziae142. DOI: 10.1093/jbmrpl/ziae142

Astleford-Hopper K, Saavedra F, Bittner-Eddy P, Stein C, Auger J, Clark R, Abrahante Llorens JE, Binstadt BA, Thumbigere-Math V, Mansky KC. 2025. Female Mice Lacking LSD1 in Myeloid Cells Are Resistant to Inflammatory Bone Loss. Cells. 14(14):Article 1111. DOI: 10.3390/cells14141111

Bachour PC, Klabunde RT, Grünheid T. 2025. Usefulness of an artificial intelligence-assisted indirect bonding method for optimizing orthodontic bracket positioning. Angle Orthodontist. 96(1):93-99. DOI: 10.2319/022425-157.1

Boivin WG, Cory MT, Kormas I, Wolff LF. 2025. Adjunctive Local Agents to Subgingival Instrumentation in the Treatment of Periodontitis: A Review of Recent Clinical Trials and Future Perspectives. Pharmaceutics. 17(6):Article 697. DOI: 10.3390/pharmaceutics17060697

Chatzopoulos GS, Wolff LF. 2025. Assessing the Long-Term Survival of Dental Implants in A Retrospective Analysis: Immediate Versus Delayed Placement. Clinical and Experimental Dental Research. 11(1):Article e70096. DOI: 10.1002/cre2.70096

Chatzopoulos GS, Wolff LF. 2025. Comparative Effect of Different Preoperative Antibiotics on Dental Implant Failure: A Retrospective Cohort Study. International dental journal. 75(3):1929-1935. DOI: 10.1016/j.identj.2025.01.012

Chatzopoulos GS, Wolff LF. 2025. Effect of antiplatelet and anticoagulant medications on implant survival: a long-term retrospective cohort study. Oral and Maxillofacial Surgery. 29(1):Article 43. DOI: 10.1007/s10006-025-01341-7

Chatzopoulos GS, Wolff LF. 2025. Is there any relation between proton pump inhibitors and risk of dental implant failure? A large-scale retrospective study using the BigMouth repository. British Journal of Oral and Maxillofacial Surgery. 63(3):239-245. DOI: 10.1016/j.bjoms.2025.01.003

Chatzopoulos GS, Wolff LF. 2025. No association between periodontitis extent, severity, and progression rate with dental implant failure. Journal of Stomatology, Oral and Maxillofacial Surgery. 126(4):Article 102123. DOI: 10.1016/j.jormas.2024.102123

Clark R, Keesler R, Ali A, MacChietto M, Munro SA, Uppgaard R, Bradley E, Tasca A, Mansky K. 2025. Skeletal site-specific variations in myeloid cells: Insights from single-cell RNA sequencing of the mandible and femur. JBMR Plus. 9(7):Article ziaf074. DOI: 10.1093/jbmrpl/ziaf074

Das A, Saeki K, Dell'Orso S, Wang X, Mansky KC, Stains J, Ozato K, Deng HW, Thumbigere-Math V. 2025. Integrative single-cell RNA-seq and ATAC-seq identifies transcriptional and epigenetic blueprint guiding osteoclastogenic trajectory. Journal of Bone and Mineral Research. 40(10):1127-1143. DOI: 10.1093/jbmr/zjaf084

Demir E, İlgenli I, Guney Z, Mohammadi S, Lauwens K, Yakar N, Alvarez Rivas C, Unlu O, Kantarci A. 2025. Maresin 1 Resolves Inflammation and Aids Bone Healing in Periapical Lesions. Journal of dental research. DOI: 10.1177/00220345251399558

Dönmez MF, Balci N, Sunkar AE, Toygar H, Kantarcı A. 2025. Taurine levels in periodontitis: A pilot study. Journal of periodontology. 96(9):984-993. DOI: 10.1002/JPER.24-0574

Furquim CP, Caruth L, Chandrasekaran G, Cucchiara A, Kallan MJ, Martin L, Feres M, Bittinger K, Divaris K, Glessner J, Kantarci A et al. 2025. Developing Predictive Models for Periodontitis Progression Using Artificial Intelligence: A Longitudinal Cohort Study. Journal of clinical periodontology. 52(10):1478-1490. DOI: 10.1111/jcpe.14194

Jones RS, Pride MA, Kumar D. 2025. An Oxymetazoline-Based Nasal Solution Removes Bacteria-Blood Debris on Dental Surfaces and Has Antimicrobial Activity Toward Streptococcus mutans. International journal of molecular sciences. 26(3):Article 1242. DOI: 10.3390/ijms26031242

Kumar D, Pride M, Mukherjee K, Jain G, Mutreja I, Jones RS. 2025. The use of oxymetazoline-based nasal solutions to remove bacteria-blood debris and eradicate Rothia dentocariosa: an artificial cavity model study. BMC Oral Health. 25(1):Article 448. DOI: 10.1186/s12903-025-05791-z

Markaryan A, Gellibolian R, Miller CS, Ebersole JL, Kantarci A. 2025. Comment on Aji et al. aMMP-8 POCT vs. Other Potential Biomarkers in Chair-Side Diagnostics and Treatment Monitoring of Severe Periodontitis. Int. J. Mol. Sci. 2024, 25, 9421. International journal of molecular sciences. 26(18):Article 9072. DOI: 10.3390/ijms26189072

Mizgier ML, Nardocci G, Ramírez V, Bendek MJ, Hernández M, Rojas C, Herrera D, Kantarci A, Kemp MW, Illanes SE et al. 2025. Proteomic Insights Into Gingival Crevicular Extracellular Vesicles in Periodontitis and Gestational Diabetes: An Exploratory Study. Journal of clinical periodontology. 52(2):225-236. DOI: 10.1111/jcpe.14083

Okumuş ÖF, Kurt N, Kantarcı A. 2025. Salivary mitofusin levels in periodontal disease: a cross-sectional case-control study. BMC Oral Health. 25(1):Article 1542. DOI: 10.1186/s12903-025-06932-0

Oner F, Kantarci A. 2025. Periodontal response to nonsurgical accelerated orthodontic tooth movement. Periodontology 2000. DOI: 10.1111/prd.12623

Oner F, Yu M, Rivas CA, Greatorex J, Zimmerman P, Guney Z, Irimia D, Davey ME, Kantarci A. 2025. Porphyromonas gingivalis sphingolipids impair neutrophil function and promote bacterial survival. Journal of Oral Microbiology. 17(1):Article 2579103. DOI: 10.1080/20002297.2025.2579103

Sahinkaya S, Yilmaz M, Yay E, Toygar H, Balci N, Altinisik DD, Kutlubay Z, Kantarci A. 2025. Behçet's disease modifies the gingival inflammatory response. Journal of periodontology. 96(4):321-329. DOI: 10.1002/JPER.24-0182

Suárez LJ, Arce RM, Furquim CP, Gonçalves C, Kantarci A, Feres M, Castro dos Santos NC. 2025. Antibiotic-mediated immune modulation in periodontitis. Periodontology 2000. DOI: 10.1111/prd.70011

Teles F, Martin L, Patel M, Hu W, Bittinger K, Kallan MJ, Chandrasekaran G, Cucchiara AJ, Giannobile WV, Stephens D, Kantarci A et al. 2025. Gingival Crevicular Fluid Biomarkers During Periodontitis Progression and After Periodontal Treatment. Journal of clinical periodontology. 52(1):40-55. DOI: 10.1111/jcpe.14061

Unlu O, Guney Z, Kantarci A. 2025. Resolvin E1 and maresin 1 restore senescence-induced disruption of human periodontal ligament fibroblast function. Journal of periodontology. 96(10):1168-1178. DOI: 10.1002/JPER.24-0565

Unlu O, Yakar N, Kantarci A. 2025. Novel and emerging antimicrobial strategies in the management of oral infections. Periodontology 2000. DOI: 10.1111/prd.70015

Vu EK, Kim G, Shimak MJ, Karkache IY, Koroth J, Chavez E, Mitchell S, Clark RB, Mansky KC, Bradley EW. 2025. Induction of Mandibular Cortical Bone Defects to Study Bone Regeneration. Endocrines. 6(1):Article 9. DOI: 10.3390/endocrines6010009

Xing Z, Liu J, Cai J, Jiang X, Liang J, Fujio M, Hadler-Olsen E, Wang J, Kantarci A, Xue Y. 2025. The Application of Resolvin D1-Loaded Gelatin Methacrylate in a Rat Periodontitis Model. Pharmaceutics. 17(1):Article 16. DOI: 10.3390/pharmaceutics17010016

Yakar N, Yilmaz B, Emingil G, Chen T, Ozdemir G, Kantarci A. 2025. Subgingival microbial profiles in pre- and postmenopausal women: Associations with serum estradiol levels. Journal of periodontology. 96(1):97-108. DOI: 10.1002/JPER.24-0267

Yılmaz B, Emingil G, Öztürk VÖ, Atmaca H, Köse T, Kantarcı A. 2025. Gingival crevicular fluid levels of TLR-9, AIM-2, and ZBP-1 in periodontal diseases. Oral Diseases. 31(3):941-948. DOI: 10.1111/odi.15108

Yılmaz B, Yıldırım Y, Yakar N, Özdemir G, Kantarci A, Emingil G. 2025. Dual-drug carboxymethyl chitosan hydrogel: Development, characterization, and in vitro evaluation for periodontal therapy. Carbohydrate Polymers. 363:Article 123726. DOI: 10.1016/j.carbpol.2025.123726

Diagnostic and Biological Sciences

Alassy H, Kersten E, Hamilton J, Botorous B, Iuorio A, Rappe TM, Costalonga M. 2025. Accuracy of Metabolomics in Peri-Implant Crevicular Fluid for Diagnosis and Prognosis of Peri-Implantitis. Journal of Periodontal Research. 60(8):775-787. DOI: 10.1111/jre.13400

Argyris PP, Dennis GR, Gopalakrishnan R, Koutlas IG, McNamara KK, Kalmar JR. 2025. Oral Soft Tissue and Jawbone Sarcomas: A Retrospective Clinicopathologic Analysis of 128 Cases from Two Institutions and Comprehensive Literature Review. Head and Neck Pathology. 19(1):Article 74. DOI: 10.1007/s12105-025-01811-0

Banik RK, Johns ME, Sia T, Simone DA. 2025. The effect of non-opioid multimodal analgesics and dexamethasone monotherapy on acute incisional pain behaviors in rats. Frontiers in Pain Research. 6:Article 1569246. DOI: 10.3389/fpain.2025.1569246

Botros J, Metzler AI, Darrow DP, Peterson CM, Montenegro MM, Nixdorf DR. 2025. Toward ICHD-4: Aligning ICHD and ICOP criteria for trigeminal autonomic cephalalgias and migraine. Cephalalgia. 45(10). DOI: 10.1177/03331024251391751

Botros J, Nixdorf DR. 2025. Orofacial trigeminal autonomic cephalalgias: A review of case reports. Cranio - Journal of Craniomandibular Practice. DOI: 10.1080/08869634.2025.2541123

Clark R, Keesler R, Ali A, MacChietto M, Munro SA, Uppgaard R, Bradley E, Tasca A, Mansky K. 2025. Skeletal site-specific variations in myeloid cells: Insights from single-cell RNA sequencing of the mandible and femur. JBMR Plus. 9(7):Article ziaf074. DOI: 10.1093/jbmrpl/ziaf074

Dargis R, Pajak J, Ariyawansa P, Morais MC, Jardine PJ, Arya G. 2025. Regulation of the ordinal DNA translocation cycle in bacteriophage Φ29 through trans-subunit interactions. Proceedings of the National Academy of Sciences of the United States of America. 122(27):Article e2504780122. DOI: 10.1073/pnas.2504780122

Domini MC, Castroflorio T, Deregibus A, Ravera S, Migliaretti G, Costalonga M. 2025. Proton-Nuclear Magnetic Resonance Metabolomics of Gingival Crevicular Fluid During Orthodontic Tooth Movement With Aligners. Orthodontics and Craniofacial Research. 28(4):670-679. DOI: 10.1111/ocr.12916

Galina IC, Romero-Servin S, Arce K, Rake A, Koutlas IG. 2025. Spontaneous Regression of Oral Kaposi Sarcoma in an HIV Negative Male. Head and Neck Pathology. 19(1):Article 97. DOI: 10.1007/s12105-025-01832-9

Gorr SU. 2025. Resisting the resistance: the antimicrobial peptide DGL13K selects for small colony variants of Staphylococcus aureus that show increased resistance to its stereoisomer LGL13K, but not to DGL13K. Journal of bacteriology. 207(6). DOI: 10.1128/jb.00505-24

Gorr SU. 2025. Targeted Modification of the Antimicrobial Peptide DGL13K Reveals a Naturally Optimized Sequence for Topical Applications. Microorganisms. 13(10):Article 2355. DOI: 10.3390/microorganisms13102355

International Network for Orofacial Pain and Related Disorders Methodology. 2025. Temporomandibular disorders: INfORM/IADR key points for good clinical practice based on standard of care. Cranio - Journal of Craniomandibular Practice. 43(1):1-5. DOI: 10.1080/08869634.2024.2405298

Jones RS, Pride MA, Kumar D. 2025. An Oxymetazoline-Based Nasal Solution Removes Bacteria-Blood Debris on Dental Surfaces and Has Antimicrobial Activity Toward Streptococcus mutans. International journal of molecular sciences. 26(3):Article 1242. DOI: 10.3390/ijms26031242

Katsoulas N, Koutlas IG, Tosios KI. 2025. A Wartin tumor-like lesion with a Wartin tumor immunophenotype. Oral Oncology. 170:Article 107728. DOI: 10.1016/j.oraloncology.2025.107728

Kohler J, Hur KH, Wray E, Donahue J, Addabbo R, Mansky LM, Mueller JD. 2025. 3D localization of retrovirus assembly in the presence of structured background with deep learning. Biophysical journal. 124(19):3256-3269. DOI: 10.1016/j.bpj.2025.08.028

Koutlas IG. 2025. Proceedings of the 2025 North American Society of Head and Neck Pathology Companion Meeting, Boston, MA, March 23, 2025: Diagnostic Borderlands in ENT Pathology—Jagulars, Heffalumps, and Cheshire Cats in Odontogenic Cysts and Tumors—How not to Feel Like Eeyore When Facing Diagnostic Odontogenic Borderlands. Head and Neck Pathology. 19(1):Article 95. DOI: 10.1007/s12105-025-01820-z

Kumar D, Pride M, Mukherjee K, Jain G, Mutreja I, Jones RS. 2025. The use of oxymetazoline-based nasal solutions to remove bacteria-blood debris and eradicate Rothia dentocariosa: an artificial cavity model study. BMC Oral Health. 25(1):Article 448. DOI: 10.1186/s12903-025-05791-z

Lindfors E, Alstergren P, Benoliel R, Conti P, Durham J, Goulet JP, Komiyama O, List T, May A, Mitsikostas DD, Nixdorf DR et al. 2025. Management of persistent idiopathic facial pain (PIFP) – An international Delphi study. Cephalalgia. 45(12). DOI: 10.1177/03331024251399927

Lyu L, Li Q, Wang C. 2025. EBV Latency Programs: Molecular and Epigenetic Regulation and Its Role in Disease Pathogenesis. Journal of Medical Virology. 97(7):Article e70501. DOI: 10.1002/jmv.70501

M. Saavedra de Paula F, Fischer LA, Bittner-Eddy PD, Johnstone KF, Stolley M, Williams DW, Herzberg MC, Costalonga M. 2025. CD69 Regulates Gingival Inflammation and Microbiome in Periodontitis. Journal of dental research. DOI: 10.1177/00220345251383827

National Dental PBRN Collaborative Group (The National Dental PBRN Collaborative Group comprises practitioners, faculty and staff investigators who contributed to this network activity). 2025. Factors Affecting Root Canal Treatment Case Difficulty, Practitioner Rating of Difficulty and Treatment Complications Among General Dentists and Endodontists: A Prospective Cohort Study From National Dental Practice-Based Research Network PREDICT Project. International Endodontic Journal. 58(12):1862-1871. DOI: 10.1111/iej.70019

National Dental PBRN Collaborative Group (The National Dental PBRN Collaborative Group comprises practitioners, faculty, and staff investigators who contributed to this network activity. A list of these persons is at;http://www.nationaldentalpbrn.org/collaborative-group.php). 2025. Prevalence and factors associated with severe pre-operative pain among patients presenting for non-surgical root canal treatment in the national dental PBRN PREDICT endodontic study. Journal of Dentistry. 163:Article 106147. DOI: 10.1016/j.jdent.2025.106147

NATIONAL DENTAL PBRN COLLABORATIVE GROUP. 2025. Characteristics of teeth and patients receiving root canal treatment in National Dental PBRN practices: Comparison between Endodontist and general dentist practices. Journal of Dentistry. 157:Article 105723. DOI: 10.1016/j.jdent.2025.105723

Nixdorf DR, Greiser A, Hayes C, Gaalaas L, Groenke BR, Fuglsig JMDCES, Johannsen KM, Herman CR, Kaimal S, Moana-Filho EJ et al. 2025. Comparison of a 0.55 T dental-dedicated magnetic resonance imaging system with a 1.5 T system in evaluation of the temporomandibular joint regarding subjective image quality assessment and rater agreement. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 140(1):113-124. DOI: 10.1016/j.oooo.2025.02.011

Nosrat A, Funkhouser E, Law AS, Abusteit O, Mungia R, Nixdorf DR, Lam EWN, Gilbert GH. 2025. Differences in clinical approaches of endodontists and general dentists when performing non-surgical root canal treatment: A prospective cohort study from the National Dental Practice-Based Research Network PREDICT Project. International Endodontic Journal. 58(9):1408-1419. DOI: 10.1111/iej.14264

Obr M, Percipalle M, Chernikova D, Yang H, Thader A, Pinke G, Porley D, Mansky LM, Dick RA, Schur FKM. 2025. Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice. Nature Structural and Molecular Biology. 32(2):268-276. DOI: 10.1038/s41594-024-01390-8

Oddo A, Abdulla F, Herold A, Tang K, Viatchenko-Karpinski V, Khasabova IA, Khasabov SG, Young M, Belcher JD, Vercellotti GM, Simone DA et al. 2025. Oral administration of a liquid containing nitrous oxide abolishes vaso-occlusive pain in mice with sickle cell disease. Haematologica. 110(12):3114-3118. DOI: 10.3324/haematol.2025.287789

Saavedra FM, Brotto DB, Joag V, Matson CA, Nesmiyanov PP, Herzberg MC, Vezys V, Masopust D, Stolley JM. 2025. Triggering mouth-resident antiviral CD8+ T cells potentiates experimental periodontitis. Mucosal Immunology. 18(3):620-630. DOI: 10.1016/j.mucimm.2025.02.003

Sikdar R, Beauclaire MV, Herzberg MC, Lima BP, Elias MH. 2025. N-acyl homoserine lactone signaling modulates bacterial community associated with human dental plaque. NPJ biofilms and microbiomes. 11(1):Article 204. DOI: 10.1038/s41522-025-00846-z

Tanwar H, Gnanasekaran JM, Ganesh N, Zhou C, Plotkin A, Baima G, Costalonga M, Zhou F, Feng H, Jani P et al. 2025. Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease. Journal of periodontology. DOI: 10.1002/jper.70045

Uttech SK, Ordinola-Zapata R, Noblett WC, Martell M, Lima B, Staley C. 2025. Multispecies Biofilms Treated With Endodontic Sealers or Calcium Hydroxide: Antimicrobial Activity and Changes in Community Composition. International Endodontic Journal. 58(11):1764-1773. DOI: 10.1111/iej.70015

Wang C, Leong MM, Ding W, Narita Y, Liu X, Wang H, Yiu SPT, Lee J, Zhao KRS, Cui A et al. 2025. Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization. EMBO Reports. 26(3):810-835. DOI: 10.1038/s44319-024-00357-6

Woodson M, Prokhorov NS, Scott SD, Zhao W, Zhang W, Choi KH, Jardine PJ, Morais MC. 2025. Phi29 assembly intermediates reveal how scaffold interactions with capsid protein drive capsid construction and maturation. Science Advances. 11(12):Article eadk8779. DOI: 10.1126/sciadv.adk8779

Primary Dental Care

Ahmad M, Gaalaas L. 2025. Imaging of Tumor-like and Cyst-like Lesions of the Temporomandibular Joints. Neuroimaging Clinics of North America. 35(4):517-526. DOI: 10.1016/j.nic.2025.06.005

Anderson H, Jackson S, Arnett MC. 2025. A Guide to Applying Motivational Interviewing in Nutritional Counseling in Dental Hygiene Education. Journal of Dental Hygiene. 99(3):51-58.

Anderson H, Rulli D, Sutton JD, Theis-Mahon N, Arnett MC. 2025. A Narrative Review of the Utilization of Motivational Interviewing for Nutritional Counseling in Dentistry. Journal of Dental Hygiene. 99(3):38-50.

Arnett MC, Cullen J, Bray K. 2025. Motivational Interviewing in Dental Hygiene Education: Past Lessons, Present Practices, and Future Directions. Journal of Dental Hygiene. 99(3):5-11.

Arnett MC, Paulson DR, Evans MD, Reibel YG. 2025. Longitudinal Impact of Brief Motivational Interviewing on Periodontal Clinical Outcomes and Patient Perceptions: A 3-year follow-up study. Journal of Dental Hygiene. 99(3):12-23.

Conrad HJ, Trauger KA, Medina J, Wang Q, John MT, Schiffman EL. 2025. Impact of maxillofacial prosthetic rehabilitation on oral health-related quality of life for patients with oral cancer: A prospective case series. Journal of Prosthetic Dentistry. 134(5):1997.e1-1997.e7. DOI: 10.1016/j.prosdent.2025.07.012

Flavin K, Paulson DR, VanDeWiele M, Evans M, Stull C. 2025. Oral health status and oral health-related quality of life among a convenience sample of individuals receiving inpatient psychiatric care: a retrospective cross-sectional study. BMC Oral Health. 25(1):Article 1135. DOI: 10.1186/s12903-025-06499-w

Flynn PM, Stull C, Jain VM, Evans MD. 2025. A national cross-sectional study of dentists' vaccine hesitancy and intention to provide HPV vaccines following emergency COVID-19 vaccination authorization. Vaccine. 53:Article 127035. DOI: 10.1016/j.vaccine.2025.127035

Fuertes RR, Arnett MC, Evans MD, Eagle IT, Cloet WJ, Herringer A, Reibel YG, Chan HL, Chiego DJ, Sweier DG et al. 2025. Periodontal Endoscope as an Educational Tool to Improve Hygiene Students’ Tactile Detection and Instrumentation Skills. Journal of dental education. DOI: 10.1002/jdd.70047

Garcia MN, Rocha-Sanchez SM, Joy-Thomas A, Zarkowski P, Kytridou V, Quick KK. 2025. Gender-based dynamics in the 2022 ADEA Climate Study: Perspectives of faculty, staff, and administrators. Journal of dental education. 89(5):712-721. DOI: 10.1002/jdd.13726

Ingleshwar Aparna, John Miket, Chantavisouk Phonsuda, Theis-Mahon Nicole, Paulson Danna R. 2025. Oral Health Impact of Dental Hygiene and Dental Therapy Patient Populations—An Evidence Update in 2024. Journal of Evidence-Based Dental Practice. 25(1):Article 102083. DOI: 10.1016/j.jebdp.2024.102083

Jessani A, Athanasakos A, Tiwari T. 2025. An Adapted Behavioral Framework for Integrating LGBT+ in Dental Curriculum: Learner-Centered Training to Person-Centered Care. Journal of dental education. 89(11):1611-1616. DOI: 10.1002/jdd.13887

Jessani A, Gansky SA, Ramos-Gomez F, Albino J, Tiwari T. 2025. Whose Data Are They? Data Ownership and Sovereignty in Oral Health Research. JDR Clinical and Translational Research. Article 23800844251382488. DOI: 10.1177/23800844251382488

Lawal Folakeb, John Miket, Oladayo Abimbolam, Paulson Danna R, Theis-Mahon Nicole, Ingleshwar Aparna. 2025. Oral Health Impact Among Children: A Systematic Review Update in 2024. Journal of Evidence-Based Dental Practice. 25(1):Article 102082. DOI: 10.1016/j.jebdp.2024.102082

Morcilio M, Reibel YG, Theis-Mahon N, Thelen RM, Arnett MC. 2025. Oral and General Health Implications of Alcoholism: A review of the literature. Journal of Dental Hygiene. 99(1):41-54.

Nixdorf DR, Greiser A, Hayes C, Gaalaas L, Groenke BR, Fuglsig JMDCES, Johannsen KM, Herman CR, Kaimal S, Moana-Filho EJ et al. 2025. Comparison of a 0.55 T dental-dedicated magnetic resonance imaging system with a 1.5 T system in evaluation of the temporomandibular joint regarding subjective image quality assessment and rater agreement. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 140(1):113-124. DOI: 10.1016/j.oooo.2025.02.011

Oliveira RCGD, Khalid H, Zhang Z, Chakraborty S, Benzano D, Kruger JS, McKernan SC. 2025. Visit Characteristics Associated With Pediatric Dental Appointment No-Shows in an Academic Dental Setting. International Journal of Dentistry. 2025(1):Article 2114933. DOI: 10.1155/ijod/2114933

Paulson Danna R, Ingleshwar Aparna, Theis-Mahon Nicole, Lin Lifeng, John Miket. 2025. The Correlation Between Oral and General Health-Related Quality of Life in Adults: A Systematic Review and Meta-Analysis. Journal of Evidence-Based Dental Practice. 25(1):Article 102078. DOI: 10.1016/j.jebdp.2024.102078

Pellegrom J, Pickett K, Kostbade G, Tiwari T. 2025. Social Vulnerability Index and Dental Caries in Children: An Exploratory Study. JDR Clinical and Translational Research. 10(2):190-197. DOI: 10.1177/23800844241279566

Perdigão J, Chew HP, Lee IK, Woodis KHatch B. 2025. Prospective, randomized clinical trial evaluating the clinical performance of a new universal adhesive in Class I and Class II restorations at 1 year. Clinical oral investigations. 29(1):Article 38. DOI: 10.1007/s00784-024-06121-3

Puri A, Wuertz B, Rhodus NL, Ondrey FG. 2025. Safety of oral mucosal punch biopsy and other oral biospecimen collections in clinical research. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 139(3):344-351. DOI: 10.1016/j.oooo.2024.10.084

Quick KK, Thelen RM, Larson GL, Jiang Z, Brady M, Garcia MN. 2025. Academic environment satisfaction and gender—Student perceptions and experiences. Journal of dental education. 89(5):743-752. DOI: 10.1002/jdd.13715

Reibel Y, Jiang Z, Arnett MC. 2025. Mentor Like Minnesota: Outcomes of an undergraduate research mentorship program. Journal of Dental Hygiene. 99(2):48-54.

Reibel YG, Hassan M, Arnett MC. 2025. DIY Orthodontic Relapse Correction Gone Wrong: A case study. Journal of Dental Hygiene. 99(1):55-62.

Schroeder KL, Heaton LJ, Martin P, Cheung HJ, Tranby EP, Rafia K, Tiwari T. 2025. Perspectives and experiences with equitable data collection in oral health: a qualitative investigation. BMC Oral Health. 25(1):Article 1090. DOI: 10.1186/s12903-025-06388-2

Stull C, Lei F, North S. 2025. First-year health professions students’ interprofessional identity development following participation in a brief introductory interprofessional activity: a qualitative study. Journal of interprofessional care. 39(5):726-735. DOI: 10.1080/13561820.2024.2391353

Stull CL, Rogers K, Flavin K, Thelen R, Evans MD, Arnett MC. 2025. Utilization of the HPV Brief Motivational Interviewing Skills-Based Training Among University of Minnesota Dental Hygiene Alumni. Journal of Dental Hygiene. 99(3):24-37.

Thelen RM, Reibel YG, Evans MD, Gietzen L. 2025. Utilization of Simulated Competency Exams in Dental Hygiene Education. Journal of dental education. 89(11):1562-1570. DOI: 10.1002/jdd.13891

Timms L, Choi S, Marshman Z, Rodd H, Wilson AR, Tiwari T. 2025. Parental acceptability of silver diamine fluoride: The UK and US experiences. International Journal of Paediatric Dentistry. 35(1):13-21. DOI: 10.1111/ipd.13195

Tiwari T, Kondratenko M, Nasiha N, Ong T, Chandrasekaran S, Kostbade G, Giano Z. 2025. Evaluating the completeness of electronic health records in dental education: a big data study. Frontiers in Oral Health. 6:Article 1535164. DOI: 10.3389/froh.2025.1535164

Tiwari T, Nowak H, Russell T, Albino A, Rivera W, Tobey T, Dye BA. 2025. Evaluating Student Communication Skills in a Simulation Setting: A Trends Analysis. Journal of dental education. DOI: 10.1002/jdd.70042

Tiwari T, Patel JS, Nascimento GG. 2025. Big Data and Oral Health Disparities: A Critical Appraisal. Journal of dental research. 104(2):119-130. DOI: 10.1177/00220345241285847

Tiwari T, Wright CD, Heaton LJ, Santoro M, Tranby EP. 2025. Dental anxiety and oral health in American Indian and Alaska natives. Journal of Public Health Dentistry. 85(2):192-196. DOI: 10.1111/jphd.12633

VanDeWiele MD, Hastings AM, Evans MD, O’Connell MS, Flynn PM. 2025. Using the Unified Theory of Acceptance and Use of Technology (UTAUT) to predict the behavioral intent of teledentistry utilization amongst United States adults. Journal of Telemedicine and Telecare. 31(2):286-296. DOI: 10.1177/1357633x231182405

Zoschke IN, Bennis SL, Tang Y, Wilkerson JM, Stull CL, Nyitray AG, Khariwala SS, Nichols CM, Rosser BRS, Flash CA et al. 2025. The influence of tobacco use, hazardous drinking, and other risk factors on HPV-associated oropharyngeal cancer risk and screening perceptions among gay and bisexual men: a cross-sectional study. BMC Oral Health. 25(1):Article 462. DOI: 10.1186/s12903-025-05774-0

Restorative Sciences

Ahmed N, Abbasi MS, Salahuddin A, Tariq L, Siraj S, Das G, Suleman G, Vohra F, Heboyan A. 2025. Comparative Analysis of Adhesive Retention and Denture Weight in Different Residual Ridge Morphologies: A Cross-Over Randomized-Controlled Trial. Clinical and Experimental Dental Research. 11(1):Article e70118. DOI: 10.1002/cre2.70118

Akl MA, Dashtti H, Akl J, Zheng F. 2025. Effect of crystallization temperature on the flexural strength of lithium disilicate glass ceramics. Journal of Prosthodontics. 34(5):527-532. DOI: 10.1111/jopr.14028

Albaijan R, Vohra F, Alnassar TM, Robaian A, Alnafaiy SM, Alzahrani KM, Alnasser AH, Alshehri A, Alkahtani R, Alrahlah A, Vorha F et al. 2025. Assessment of surface micro-roughness and de-torque of selective laser melting, cast, and machined implant abutments: An in vitro study. Journal of Prosthodontics. DOI: 10.1111/jopr.70012

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights into the April 2025 Issue of the JOE. Journal of Endodontics. 51(4):397-398. DOI: 10.1016/j.joen.2025.03.006

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights Into the Aug 2025 Issue of the JOE. Journal of Endodontics. 51(8):983-985. DOI: 10.1016/j.joen.2025.07.010

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights Into the December 2025 Issue of the JOE. Journal of Endodontics. 51(12):1697-1699. DOI: 10.1016/j.joen.2025.11.001

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights into the February 2025 Issue of the JOE. Journal of Endodontics. 51(2):103-105. DOI: 10.1016/j.joen.2025.01.017

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights Into the January 2025 Issue of the Journal of Endodontics. Journal of Endodontics. 51(1):1-3. DOI: 10.1016/j.joen.2024.12.005

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights into the July 2025 Issue of the JOE. Journal of Endodontics. 51(7):825-827. DOI: 10.1016/j.joen.2025.06.007

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights into the June 2025 Issue of the JOE. Journal of Endodontics. 51(6):655-657. DOI: 10.1016/j.joen.2025.05.017

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights into the March 2025 Issue of the JOE. Journal of Endodontics. 51(3):255-257. DOI: 10.1016/j.joen.2025.02.005

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights into the May 2025 Issue of the JOE. Journal of Endodontics. 51(5):535-537. DOI: 10.1016/j.joen.2025.05.001

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights Into the November 2025 Issue of the JOE. Journal of Endodontics. 51(11):1505-1507. DOI: 10.1016/j.joen.2025.10.003

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights into the October 2025 Issue of the JOE. Journal of Endodontics. 51(10):1339-1341. DOI: 10.1016/j.joen.2025.09.005

Aminoshariae A, Azarpazhooh A, Glickman GN, He J, Kim SG, Kishen A, Letra AM, Levin L, Ordinola-Zapata R, Setzer FC et al. 2025. Insights Into the September 2025 Issue of the JOE. Journal of Endodontics. 51(9):1133-1135. DOI: 10.1016/j.joen.2025.08.007

Cho-Kee D, Basrani BR, Vera J, Ordinola-Zapata R, Aguilar RR. 2025. Sodium Hypochlorite Accidents: A Retrospective Case-series Analysis of CBCT Imaging and Clinician Surveys. Journal of Endodontics. 51(10):1485-1489. DOI: 10.1016/j.joen.2025.05.024

Conrad HJ, Trauger KA, Medina J, Wang Q, John MT, Schiffman EL. 2025. Impact of maxillofacial prosthetic rehabilitation on oral health-related quality of life for patients with oral cancer: A prospective case series. Journal of Prosthetic Dentistry. 134(5):1997.e1-1997.e7. DOI: 10.1016/j.prosdent.2025.07.012

Conrad HJ. 2025. Annual report of the American Board of Prosthodontics. Journal of prosthodontics : official journal of the American College of Prosthodontists. 34(1):3-4. DOI: 10.1111/jopr.14010

Fontana G, Nemke B, Lu Y, Chamberlain C, Lee JS, Choe JA, Jiao H, Nelson M, Amitrano M, Li WJ et al. 2025. Local delivery of TGF-β1-mRNA decreases fibrosis in osteochondral defects. Bioactive Materials. 45:509-519. DOI: 10.1016/j.bioactmat.2024.11.033

Gantier-Takano MK, Xing Y, Ye N, Aparicio C, Navarro Cuéllar C, Meira JBC, Fok ASL. 2025. Microgap Formation in Conical Implant-Abutment Connections Under Oblique Loading: Influence of Cone Angle Mismatch Through Finite Element Analysis. Clinical Implant Dentistry and Related Research. 27(1):Article e13436. DOI: 10.1111/cid.13436

Gialain IO, Gantier-Takano MK, da Silva LFR, Roscoe MG, Pinhata-Baptista OH, Meira JBC, Fok ASL. 2025. A finite element study on the risk of bone loss around posterioshort implants in an atrophic mandible. Journal of Prosthodontic Research. 69(1):110-119. DOI: 10.2186/jpr.JPR_D_24_00003

Goldschmidt S, Chew HP, Guy S, Fok A. 2025. Characterizing masticatory motion of dogs using optical and electromagnetic motion tracking. Frontiers in Veterinary Science. 12:Article 1625335. DOI: 10.3389/fvets.2025.1625335

González-Alenda E, Baracco B, Perdigão J, Jiménez-Díez D, Garrido MÁ, Álvarez-Lloret P, Ceballos L, Fuentes V. 2025. Physicomechanical Properties and Morphological Characterization of Several Universal Resin Composites After Different Aging Procedures. Journal of Esthetic and Restorative Dentistry. 37(12):2533-2545. DOI: 10.1111/jerd.70010

Hellenbrand DJ, Lee JS, Mickelson EJ, Baer MC, Ott EL, Martinson NR, Celeen MR, Hilger KH, Nielsen BE, Jacobs AN et al. 2025. Mineral coated microparticles delivering Interleukin-4, Interleukin-10, and Interleukin-13 reduce inflammation and improve function after spinal cord injury in a rat. Experimental Neurology. 386:Article 115179. DOI: 10.1016/j.expneurol.2025.115179

Kumar D, Pride M, Mukherjee K, Jain G, Mutreja I, Jones RS. 2025. The use of oxymetazoline-based nasal solutions to remove bacteria-blood debris and eradicate Rothia dentocariosa: an artificial cavity model study. BMC Oral Health. 25(1):Article 448. DOI: 10.1186/s12903-025-05791-z

Lin F, Ordinola-Zapata R, VanHeel B, Zhang L, Lee R, Ye Z, Xu H, Fok ASL. 2025. Experimental investigation and finite element analysis on the durability of root-filled teeth treated with multisonic irrigation. Dental Materials. 41(3):341-346. DOI: 10.1016/j.dental.2024.12.009

Mays K, Lee A, Forester R, Brear S. 2025. The American Dental Education Association 2022 Climate Study Recommendations and Strategic Actions. Journal of dental education. 89(5):798-804. DOI: 10.1002/jdd.13833

Mays KA, Ouyang I, Cooper A, Wang Q. 2025. Finances and employment domains are strong determinants when screening for unmet social needs in a predoctoral dental clinic: A preliminary assessment. Journal of dental education. 89(4):476-484. DOI: 10.1002/jdd.13776

Miranda NCF, Gialain IO, Gantier-Takano MK, Ballester RY, Hernandez BA, Fok A, Meira JBC. 2025. Should the load-to-fracture test for CAD/CAM monolithic molar crowns be standardized and how? A systematic review and finite element analysis. Journal of the Mechanical Behavior of Biomedical Materials. 168:Article 106984. DOI: 10.1016/j.jmbbm.2025.106984

Nirkhiwale A, Tartar W, Mays KA. 2025. An Analysis of Student's Perspective of an Early Team-Based Denture Clinical Experience. Journal of dental education. 89(11):1593-1600. DOI: 10.1002/jdd.13883

Nixdorf DR, Greiser A, Hayes C, Gaalaas L, Groenke BR, Fuglsig JMDCES, Johannsen KM, Herman CR, Kaimal S, Moana-Filho EJ et al. 2025. Comparison of a 0.55 T dental-dedicated magnetic resonance imaging system with a 1.5 T system in evaluation of the temporomandibular joint regarding subjective image quality assessment and rater agreement. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 140(1):113-124. DOI: 10.1016/j.oooo.2025.02.011

Patel S, Teng PH, Liao WC, Davis MC, Fidler A, Haupt F, Fabiani C, Zapata RO, Bose R. 2025. Position statement on longitudinal cracks and fractures of teeth. International Endodontic Journal. 58(3):379-390. DOI: 10.1111/iej.14186

Perdigão J, Chew HP, Lee IK, Woodis K, Hatch B. 2025. Prospective, randomized clinical trial evaluating the clinical performance of a new universal adhesive in Class I and Class II restorations at 1 year. Clinical oral investigations. 29(1):Article 38. DOI: 10.1007/s00784-024-06121-3

Perdigão J, Zatt FP, Lopes GC, Caon NB, Chen R. 2025. Characterization of Universal Composite Resin Filler Particles. Journal of Esthetic and Restorative Dentistry. 37(11):2472-2480. DOI: 10.1111/jerd.70009

Queiroz DA, Freitas MIM, Ockey KT, Lee DJ, Zheng F. 2025. Reverse Torque and Wear of Internal Connections of Metal-Based Abutments Under Cyclic Loading. Journal of Esthetic and Restorative Dentistry. 37(6):1539-1545. DOI: 10.1111/jerd.13425

Uttech SK, Ordinola-Zapata R, Noblett WC, Martell M, Lima B, Staley C. 2025. Multispecies Biofilms Treated With Endodontic Sealers or Calcium Hydroxide: Antimicrobial Activity and Changes in Community Composition. International Endodontic Journal. 58(11):1764-1773. DOI: 10.1111/iej.70015

Vievering J, Ong S, Fok A, Labuz JF, Le JL. 2025. Experimental Characterization of Spatial Randomness of Elastic Properties of Heterogeneous Materials. Experimental Mechanics. 65(8):1341-1355. DOI: 10.1007/s11340-025-01218-6

Wan Hassan WN, Tee YY, Md Razali K, Abdul Razak AA, Lim HH, Zakaria N, Sukumaran P, Mohd Tahir NNZ, Chew HP. 2025. A 12-months randomized clinical trial comparing fluoride-based remineralising protocols on post-orthodontic initial caries lesions. Clinical oral investigations. 29(2):Article 111. DOI: 10.1007/s00784-025-06172-0

Graduate Student and Resident Grant Awards

Dual Degree | DDS/PhD in Oral Biology

Sarah Aitken. Binding Specificity and Transcriptional Regulation of Antigen I/II Adhesins in Streptococcus Gordonii. National Institutes of Health National Institute of Dental and Craniofacial Research Grant. F30. Awarded 14 August 2025.

 

PhD in Biochemistry, Molecular Biology and Biophysics

Bill Arndt. Structural characterization of the HIV-2 capsid lattice. National Institutes of Health National Institute of Allergy and Infectious Diseases Grant. F31. Awarded 27 September 2025.

Electron micrographs of bacterial viruses, also known as phages

A MIGHTY undertaking

University of Minnesota researchers lead key effort in up to $28M ARPA-H project to harness phages to enhance human health 

Contact the Office of Research and Discovery

Kristin Artinger, PhD

Associate Dean for Research and Discovery
Kristin Artinger, PhD

612-626-5731
[email protected]