Nelson Rhodus, DMD, MPH

Nelson L, Rhodus, DMD, MPH, is a Distinguished Professor and Director of the Division of Oral Medicine, Oral Diagnosis and Radiology in the Department of Diagnostic and Surgical Sciences in the University of Minnesota School of Dentistry. He is a Diplomate of the American Board of Oral Medicine, and Director of the Oral Medicine and Xerostomia Clinics. He is an attending member of the Hospital Staff of Fairview-University Medical Center and the Minnesota Cancer Center, and a consultant to the Veteran's Hospital and Hennepin Co. Medical Center.

Dr. Rhodus directs several Physical Evaluation and Introduction to Oral Pathology courses. He has been awarded "Faculty of the Year" for 13 consecutive years and is a recipient of the School of Dentistry Century Club Professor of the Year. He is active in basic and clinical research with oral manifestations of systemic disease and chronic degenerative autoimmune diseases. He serves on the national medical advisory board of the National Sjogren's Syndrome Association. He has received numerous research grants and is a member of the Minnesota Dental Research Institute and the International Association for Dental Research.

Dr. Rhodus has presented over 200 lectures and courses throughout the United States and abroad. He has published over one hundred seventy scientific papers and abstracts and has been the recipient of the "Outstanding Clinician Award" five times from three different state dental associations, Kentucky (1979), Oklahoma (1985), and Minnesota (1987, 1988, 1989). He is a recipient of the Morse Distinguished Professor Award, the Pierre Fauchard Academy Award, the American Academy of Oral Medicine's Meritorious Service Award, the University of Kentucky Distinguished Alumnus Award, the American Cancer Society's Meritorious Service Award, and is an inductee into Omicron Kappa Upsilon and is listed in Who's Who in America, Who's Who in American Education, and Men of Achievement, Cambridge, England.

Dr. Rhodus enjoys running marathons, triathlons, tennis, golf, skiing, fishing and basketball.

Oral cancer: early detection and chemoprevention
Oral manifestations of systemic disease
Chronic degenerative autoimmune diseases
Sjögren's Syndrome

Academic Interests and Focus:
Physical evaluation; Introduction to oral pathology

Men of Achievement, Cambridge, England

Award for Education, American Dental Society of Anesthesiology

USA Top Dentist

Little-Falace Award ( AAOM) for Distinction in Scientific Publications

Best Dentist-Minnesota Monthly

Induction into The Royal College of Surgeons of Edinburgh, Scotland

University of Kentucky College of Dentistry Distinguished Alumnus Award

Lifetime Achievement Award for Teachers of Oral Diagnosis, AAOM

America’s Top Dentists, Minnesota Top Dentists

Distinguished Service Award, King Faisel Hospital, Riyahd, Saudi Arabia

America’s Top Dentists, Minnesota Top Dentists

AR Diamond Pin Lifetime Achievement Award, AAOM

Samuel Charles Miller Award, AAOM

America’s Top Dentists, Minnesota Top Dentists

Academy of Excellence in Scholarship of Teaching, UM Academic Health Center

International College of Dentists-Fellow-Inductee

International College of Dentists-Golden Pen Award-Northwest Dentistry

American College of Dentists-Fellow-Inductee

University of Minnesota Scholars Walk of Fame-Inductee

Distinguished Service Award-AAOP-AAOM

International College of Dentists-Golden Pen Award-Northwest Dentistry

Dr. Joe Gibilisco Distinguished Lecturer Mayo Clinic

Bush Fellowship Resource Professor Award

Bush Fellowship Resource Professor Award

University of Minnesota Academy of Distinguished Teachers, Inductee

Morse Alumni Distinguished Professor Award for Graduate and Professional Education

Outstanding Professor Award

CENTURY CLUB PROFESSOR of the YEAR

Distinguished Alumnus, University of Kentucky College of Dentistry

Overall Most Outstanding Instructor of Dental School Career, From Class of 1995

Outstanding Contribution to Professional Education, American Cancer Society

Outstanding Contribution to Professional Education, American Cancer Society

Minnesota Dental Association Star of the North , Outstanding Clinician Award

Outstanding Clinician Award, Minnesota Dental Association Star of the North

Award of Merit, Sjogren's Syndrome Foundation

Outstanding Clinician Award, Minnesota Dental Association Star of the North

Outstanding Professor Award

Award of Merit , American Academy of Oral Medicine

Who's Who of Emerging Leaders in America

University of Minnesota Alumni Day

Who's Who In the Midwest

Who's Who of Emerging Leaders in America

Outstanding Professor Award

Outstanding Clinician Award, Minnesota Dental Association Star of the North

Outstanding Professor Award

Table Clinic Award, Oklahoma Dental Association

Outstanding Full-time Faculty, Oral Robert’s University

Seids Cup Award - Outstanding Clinician, Oklahoma Dental Association

Outstanding Professor Award, Oral Robert’s University

Table Clinic Award, Tulsa County Dental Society

Table Clinic Award, Tulsa County Dental Society

Table Clinic Award, Oklahoma Dental Association

Kay County Dental Society Appreciate Award, Oklahoma Dental

Table Clinic Award, Tulsa County Dental Society

Table Clinic Award, Oklahoma Dental Association

Kiwanis International Merit Award

Kentucky Volunteer Service Award of Merit

Governor's Merit Award , Kentucky Council of Volunteer Services

Dean's Letter of Commendation, University of Kentucky, College of Dentistry

Dental Student Research Award, American Dental Association Dental Student Research Award

Pierre Fauchard Academy Award of Merit

American Dental Society of Anesthesiology National Award

American Student Dental Association Merit Award

Undergraduate Student Award, University of Kentucky College of Dentistry

Bluegrass Table Clinic Award

Scholarship Award

Governor's Merit Award - High School Valedictorian

THE CANCER POETRY PROJECT, Fairview Press, 2001

Sjogren’s syndrome, Murray Hill Studios , NYC, 2000

University of Minnesota Cancer Center, MINNESOTA PUBLIC RADIO, 1999

Oral Cancer, KAAL-TV, 1999

Health Talk and You, University of Minnesota Hospital regional network, 1993

Update on Sjögren’s Syndrome, LIFETIME, 1988

American Board of Oral Medicine, Treasurer

American Academy of Oral Medicine National Officer, President-Elect

American Academy of Oral Medicine, Board of Trustees

Royal College of Surgeons of Edinburgh, Fellow-International

College of Dentists

American Academy of Oral Medicine, President

American College of Dentists, Fellow

Sjogren's Syndrome Foundation National Board of Directors

Minnesota Dental Association

American Dental Association

American Association of Dental Schools

Organization of Teachers of Oral Diagnosis

Pierre Fauchard Academy

University of Minnesota Academy of Distinguished Teachers, Director

Lupus Foundation Medical Advisory Board

Omicron Kappa Upsilon Honorary Fraternity

National Sjogren’s Syndrome Association, Medical Advisory Board

American Dental Society of Anesthesiology

National Oral Cancer Foundation, Medical Advisory Board

International Association for Dental Research-American Association for Dental Research

American Association of University Professors, President - UMTC

2004. Over expression of Interferon induced genes and down-regulation of Aquaporin 1 in the blood of patients with Sjogren’s syndrome.

Guidebook for the Management of Medical Emergencies in the Dental Office. NORTHWEST DENTISTRY, 65 (3): 8. United States:

Protein Profiles in Whole and Parotid Saliva From Sjogren's Syndrome Patients. JOURNAL of DENTAL RESEARCH, 68 (3): 404. United States:

An Unusual Vertical Root Fracture. ORAL SURGERY, ORAL MEDICINE AND ORAL PATHOLOGY, 71 (3): 376. United States:

A clinical evaluation of a commercially available oral moisturizer in relieving the signs and symptoms of xerostomia in post-irradiation therapy and Sjogren’s syndrome patients. JOURNAL of OTOLARYNGOLOGY, 29 (1): 1-7. United States:

An Update on the management of dental patients with cardiac arrhythmias. Oral Surg Oral Med Oral Path Oral Radiol Endo, 96 (6): 659-65. United States:

Characterizing oral cancer progression by free flow electrophoresis-based quantitative saliva proteomics. J. Molecular and Cell Proteomics, 7 (3): 486-498. Untied States:

Evaluating the potential of a novel oral lesion exudate collection method coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery. Journal of Clinical Proteomics, United States:

doi: https://doi.org/8:13 doi:10.1186/1559

Sjögren’s syndrome-associated transcripts show correlation with objective measures of dryness.

Identification of Sjögren’s syndrome-associated long non-coding RNAs that are co-expressed with key protein-coding transcripts involved in dysregulated interferon responses..

Decreased SLPI in oral cancer detected in brush biopsy proteomics..

Functional characterization of the Sjögren’s syndrome-associated locus DDX6-CXCR5. Arthritis and Clinical Immunology.

Functional characterization of the Sjögren’s syndrome-associated locus DDX6-CXCR5. Arthritis and Clinical Immunology..

Performance and Reliability of the Ocular Staining Score (OSS) vs. the van Bijsterveld Score in the assessment of Sjögren’s Syndrome-related keratoconjunctivitis sicca Arthritis and Clinical Immunology.

Contributing Author to: Prevention Publications. DOCTORS HOME REMEDIES, New York, NY, United States:

Managing Allergies in Dentistry. Quintessence Press, New York, NY,

Genome-wide association study identifies novel Sjögren’s syndrome risk loci in the regions of NAB1, TYK2, and PTTG1-mir146a.

Simultaneous detection of IFN-gamma and IL-4 in whole unstimulated saliva and lesional tissues from patients with oral lichen planus. J. Oral Path. Med, (37): 83-87. United States:

Identification and characterization of Sjögren’s syndrome-associated genetic variants in the IL12A and DDX6-CXCR5 loci.

GCF levels, sulcular Candida albicans and periodontal status in patients with Sjogren's syndrome. Quintessence International, 36 (3): 228-233. United States:

Identification of Sjögren’s syndrome-associated long non-coding RNAs that are co-expressed with key protein-coding transcripts involved in dysregulated interferon responses.

Treatment of primary Sjogren’s syndrome. With low-does Natural Interferon-alfa administered by the oromucosal route. J. ARTHRITIS CARE and RES, United States:

Effect of Tobacco Smoking on the Clinical, Histopathological, and Serological Manifestations of Sjögren’s Syndrome.

Articulatory speech performance in patients with salivary gland dysfunction: a pilot study. QUINTESSENCE INTERNATIONAL, 26 (11): 805-812. United States:

Previous diagnosis of Sjögren’s Syndrome as rheumatoid arthritis or systemic lupus erythematosus.

The clinical significance of EKG screening of dental patients with a case report. NORTHWEST DENTISTRY, 68 (4): 33-43. United States:

Sample collection and handling considerations for peptidomics in whole saliva.

Quantitative Nutritional Intake Analysis of Older Adults with Sjogren's Syndrome. JOURNAL OF DENTAL RESEARCH, 67 (2): 266. United States:

Salivary amylase as a potential biomarker for oral cancer.

Update on the diagnosis and treatment of Sjogren’s syndrome and xerostomia. NORTHWEST DENTISTRY, 78 (4): 24-34. United States:

Characterization of the Sjogren’s Syndrome Intergenic Non-Coding RNA 1 (SSINCR1).

Preventive Dentistry - How to Cost Effectively Expand Your Dental Practice. DENTAL MANAGEMENT, 26 (10): 30-33. United States:

Sample collection and handling considerations for peptidomics in whole saliva.

A comparison of screening methods in two early phase oral leukoplakia clinical trials. Oral Dis, United States:

doi: doi: 10.1111/j.1601-0825.2012.01934.x.

Salivary amylase as a potential biomarker for oral cancer.

Management of the patient undergoing radiation therapy for head and neck cancer. Northwest Dentistry, 90 (1): 24-28. United States:

Identification of a Sjögren’s syndrome-associated variant that influences OAS1 isoform switching and protein expression.

Antibiotic prophylaxis in dentistry: an update. Gen Dent. J, 56 (1): 20-28. United States:

Primary Sjögren’s syndrome patients with autoantibodies against TRIM38 show greater severity of disease.

Xerostomia and hyposalivation: Detection and management. Minnesota Physician, 20 (3): 10-12, 40. United States:

Characterization of a Sjögren’s syndrome-associated long non-coding RNA at 2p25.1.

The Prevention and Treatment of Radiotherapy-Induced Xerostomia. Sem. Rad. Oncol, 13 (3): 308-315. United States:

Proteomics reveal CD44 and Mammoglobulin in the Early Detection of Recurrent Breast Cancer.

Impact of criteria-based diagnosis of Burning Mouth Syndrome on treatment outcome. Journal of Orofacial Pain, (16): 305-311. United States:

Current therapies for managing hyposalivation in Sjogren’s syndrome.

Detection and management of the hypertensive dental patient. Northwest Dentistry, 80 (3): 11-27. United States:

Outcomes form the implementation of clinical care guidelines using electronic dental records.

Oral Pilocarpine HCl stimulates labial (minor) salivary flow in patients with Sjøgren's syndrome. JOURNAL of ORAL DISEASES, 3 (6): 116-123. United States:

Proteomics reveal CD44 and Mammoglobulin in the Early Detection of Recurrent Breast Cancer.

Oral Pilocarpine for post-irradiation xerostomia in patients with head and neck cancer. NEW ENGLAND JOURNAL OF MEDICINE, 329 (6): 390-395. United States:

Sample collection and handling considerations for peptidomics in whole saliva.

Xerostomia, Drugs, Nutritional status and laboratory values in Institutionalized Older Adults. JOURNAL of ORAL SURGERY, ORAL MEDICINE and ORAL PATHOLOGY, 70 (4): 457. United States:

Identification of a Sjögren’s syndrome-associated variant that influences OAS1 isoform switching.

Oral Manifestations of Sjogren's Syndrome. NORTHWEST DENTISTRY, 67 (5): 19-20. United States:

RNA-sequencing identifies novel differentially expressed coding and non-coding transcripts in Sjögren’s syndrome. Human Genetics.

EKG screening Dentists for Cardiac Arrhythmias. JOURNAL of DENTAL RESEARCH, 68 (6): 958. United States:

Complex functional effects within the HLA contribute to Sjögren’s syndrome and may include both transcriptional regulation and peptide binding.

Managing Xerostomia. MINNESOTA SSF REPORT, 1 (3): 4-6. United States:

Complex functional effects within the HLA contribute to Sjögren’s syndrome and my include both transcriptional regulation and peptide binding.

Oral issues with Fetal Alcohol syndrome. NORTHWEST DENTISTRY, 82 (2): 7-18. United States:

Salivary Diagnostics in the Early Detection of Recurrent Breast Cancer.

Emerging Infectious Disease in Dentistry - Part I. NORTHWEST DENTISTRY, 76 (2): 11-21. United States:

Identification of a Sjögren’s syndrome-associated variant that influences OAS1 isoform switching.

A Systemic, Problem Oriented Approach to the Comprehensive Diagnosis. NORTHWEST DENTISTRY, 67 (3): 11-15. United States:

Gene expression profiling in a large cohort of Europeans with Sjögren’s syndrome reveals candidate genes in viral, immune, and interferon-related pathways.

Handbook for the Management of the Medically Compromised Dental Patient. Oral Roberts University, School of Dentistry, 121 pgs. Tulsa, Oklahoma, United States:

Electronic dental records for implementation of clinical care guidelines.

Pain in primary Sjogren’s syndrome: the Role of Catastrophizing and Negative Illness Perceptions.. Scand J Rheumatol, 67 (1): 1-8. Oslo, Norway:

doi: https://doi.org/DOI: 10.3109/03009742.2013.846409

Quantitative Proteomic Analysis Reveals Decreased Salivary Amylase in Oral Cancer.

Hexapeptide libraries for enhanced protein PTM identification and relative abundance profiling in whole human saliva. Journal of Proteome Research, 10 (3): 1052-61. United States:

Proteomics on oral lesion transudates for oral cancer biomarker discovery.

Parkinson’s disease: dental treatment considerations. Northwest Dentistry, 90 (4): 21-26. United States:

Salivary Diagnostics in the Early Detection of Recurrent Breast Cancer.

What is your diagnosis?: Osteonecrosis of the jaw. Northwest Dentistry, 889 (2): 24-28. United States:

cis-eQTL analysis of dysregulated interferon-pathway genes identifies OAS1 as a novel candidate for susceptibility to Sjögren’s syndrome.

Dental management of patients prior to head and neck cancer radiation therapy. Proceedings Society of Head and Neck Cancer, 18 (4): 1-6. United States:

Gene expression profiling in a large cohort of Europeans with Sjögren’s syndrome reveals viral, immune, and interferon-related pathways.

Pharmacologic Management of Type I Diabetes: A Review for Dentistry. Gen. Dent, 55 (5): 403-09. United States:

A genome-wide association study by the Sjögren’s Genetics Network identifies novel susceptibility loci for Sjögren’s syndrome.

Frequent Mutation of p16CDKN2A Exon1 During Rat Tongue Carcinogenesis Induced by 4-Nitroquinoline-1-Oxide. MOLECULAR CARCINOGENESIS, (46): 85-94. United States:

A genome-wide association study by the Sjögren’s Genetics Network identifies novel susceptibility loci for Sjögren’s syndrome.

NF B dependent cytokine levels in saliva of patients with oral preneoplasia and oral cancer. J. Cancer Detection and Prevention, 29 (1): 42-54. United States:

Use of Global Gene Expression Profiling to Characterize Sjögren's Patients Who Underexpress Interferon-Inducible Genes.

Epinephrine and local anesthetic revisited. Oral Surg Oral Med Oral Path Oral Radiol Endo, 100 (4): 401-404. United States:

Effects of Reclassification Using the American College of Rheumatology Criteria On a Large cohort Sjögren's Syndrome Patients.

Burning Mouth Disorder. QUINTESSENCE INTERNATIONAL, (34): 587-91. United States:

Salivary Diagnostics in the Early Detection of Recurrent Breast Cancer.

CTCAE v. 3.0 Development of a comprehensive grading system for the adverse effects of cancer treatment. Sem Radiat Oncol, 13 (3): 176-181. United States:

"RNA-Sequencing Identifies Novel Differentially Expressed Coding and Non-Coding Transcripts in Sjögren’s Syndrome".

Salivary cytokines as surrogate biomarkers in oral carcinogenesis. CANCER RES, United States:

Efficacy of pioglitozone for the treatment of oral leukoplakia.

About 8- and ~84-hour rhythms in endotheliocytes as in endothelin-1 and effect of trauma. Peptides, (22): 647-659. United States:

THE RELATIONSHIP OF FATIGUE AND NEUROPSYCHIATRIC SYMPTOMS TO ANTI-RO STATUS IN A LARGE COHORT OF SJÖGREN’S SYNDROME CASES.

Treatment of Sjogren’s syndrome with low-dose Human IFN-alpha administered by the oral mucosal route. J. CYTOKINE RESEARCH, United States:

THE EFFECT OF PREVIOUS TONSILLECTOMY ON INCIDENCE OF SJÖGREN’S SYNDROME.

Salivary s-IgA and cytokine levels in Sjogren’s patients before and after pilocarpine Hcl administration. J. Clin. Investigation, 2 (2): 1-7. United States:

GENE EXPRESSION PROFILING IN A COHORT OF 275 EUROPEAN AMERICAN SJÖGREN’S SYNDROME PATIENTS AND CONTROLS PROVIDES BETTER CHARACTERIZATION OF THE INTERFERON SIGNATURE IN THIS DISORDER.

Emerging Infectious Disease in Dentistry - Part I. Northwest Dentistry, 76 (2): 11-21. United States:

Factors Predictive of Depression in Primary Sjogren’s Syndrome (PSS).

Prevalence of oral lesions among individuals with symptomatic and asymptomatic Human Immunodeficiency Virus infection. JOURNAL of GENERAL DENTISTRY, 42 (10): 446-450. United States:

LARGE-SCALE, HIGH-DENSITY GENOTYPING PERFORMED BY THE SJÖGREN’S GENETICS NETWORK USING THE IMMUNOCHIP IDENTIFIES PRKRA AS A NOVEL SJÖGREN'S SYNDROME SUSCEPTIBILITY LOCUS AND CONFIRMS ASSOCIATIONS WITH IRF5, BLK, AND MHC.

The need for antibiotic prophylaxis of patients with penile implants during invasive dental procedures: a national survey of urologists. JOURNAL of UROLOGY, 148 (6): 1301-1305. United States:

Correlation of Minor Salivary Gland Biopsy Focal Score and Unstimulated Salivary Flow Rate in Patients with Primary Sjögren's Syndrome, Taking into Consideration Steroid Use.

Dental patient reaction to EKG screening. JOURNAL of ORAL SURGERY, ORAL MEDICINE and ORAL PATHOLOGY, 70 (7): 433-440. United States:

Early phase development of salivary proangiogenic cytokines as biomarkers in oral leukoplakia.

A Comparison of Periapical and Panoramic Radiographic Surveys in the Diagnosis of Maxillary Sinus Mucous Retention Cysts. COMPENDIUM OF CONTINUING EDUCATION IN DENTISTRY, 10 (5): 275-282. United States:

Proteomics analysis of oral epithelial cells collected by brush biopsy.

Detection and Management for the Diabetic Patient in the preventive dental practice. COMPENDIUM OF CONTINUING EDUCATION IN DENTISTRY, 8 (3): 73-79. United States:

Interferon gene expression in Sjigrena syndrome.

Dual steroid therapy for refractory oral lichen planus.

Diagnostic Utility of Labial Salivary Gland Biopsy in Sjogren's Syndrome.

GCF Volume, PMNs and Periodontal Characteristics of Sjogren's Syndrome Patients. JOURNAL of DENTAL RESEARCH, 68 (3): 283. United States:

Cataloging the human salivary proteome in health and disease.

Curricular Implicarions of the Changing Profile of a Dental School Patient Population: A Ten Year Study. JOURNAL OF DENTAL EDUCATION, 52 (1): 53. United States:

Saliva and serum cytokines in oral leukoplakia.

Nutritional Deficiencies in Patients with Sjogren's Syndrome. JOURNAL OF ORAL MEDICINE, 43 (3): 5. United States:

Metaproteomic analysis of the human salivary microbiome.

Comparison of Panoramic and Periapical Radiographs in Diagnosing MSMR Cysts. JOURNAL OF DENTAL RESEARCH, 66 (3): 1313. United States:

Retrospective analysis of oral precancerous lesions and their outcomes.

Monitoring Mercury Vapor in the Dental Office Using Selenium Sulfide Discs. JOURNAL of DENTAL RESEARCH, 64 (3): 247. United States:

Interferon-Regulated Chemokines are Biomarkers of Primary Sjogren’s Syndrome.

Detection and management of the hypertensive dental patient. NORTHWEST DENTISTRY, 80 (3): 11-27. United States:

Proinflammatory, proangiogenic cytokines in saliva and serum in oral leukoplakia.

The Dental Record. NORTHWEST DENTISTRY, 76 (5): 1-16. United States:

Oral cancer progression as determined by free flow electrophoresis-based quantitative saliva proteomics.

Candidaisis in Sjogren’s syndrome patients. SJOGREN'S SYNDROME DIGEST, 7 (3): 3-6. United States:

Interferon-regulated serum biomarkers in primary Sjögren’s syndrome.

The clinical significance of EKG screening of dental patients with a case report. NORTHWEST DENTISTRY, 68 (4): 33-43. United States:

Serum Th1/Th2 cytokies and clinical characteristics in primary Sjögren’s syndrome.

Xerostomia: An Increasingly Significant Dental Management Challenge. NORTHWEST DENTISTRY, 66 (3): 14-18. United States:

Correlative analyses of milieu inflammatory cytokines in preneoplastic oral leukoplakia.

The Increasing Need for Comprehensive Physical Evaluation and Medical Consultation in Dental Practice. NORTHWEST DENTISTRY, 65 (2): 17-22. United States:

Safety of PPAR gamma activation strategies for precancerous leukoplakia.

A Systematic Problem-Oriented Approach to the comprehensive dental patient evaluation. Oral Roberts University, School of Dentistry, 12 pgs.. Tulsa, Oklahoma, United States:

Barriers to patient accrual in oral leukoplakia clinical trials.

Effects of Corticosteroids on Minor Salivary Gland Biopsies and Whole, Unstimulated Salivary Flow in Primary Sjogren's Syndrome.. J Oral Surg Oral Med Oral Path Oral Rad Endo, United States:

Characterizing oral cancer progression by free flow electrophoresis-based quantitative saliva proteomics.

Oral Candidiasis. SSF: Moisture Seekers, 12 (6): 1-5. United States:

Gene expression profile of Sjogren’s syndrome patients: differences/similarities to SLE.

Treatment of Oral Candidasis. Northwest Dentistry, 91 (2): 32-36. United States:

Role of SLUG in head and neck squamous cell carcinoma.

The effect of electronic health records on the use of clinical care guidelines for patients with medically complex conditions. JADA, 142 1133-1142. United States:

Mast cells in Oral lichen planus: methods of histologic characterization.

Genetics of Sjogren’s Syndrome: Genomics Research provides Clues to Pathogenesis and Novel Therapies. J Oral Surg Oral Med Oral Path Oral Rad Endo, 111 (6): 673-80. United States:

Candida species of Primary Sjogren’s syndrome patients.

Novel in situ Collection of Tumor Interstitial fluid from a head and neck squamous carcinoma reveals a unique Proteome with diagnostic potential. Clinical Proteomics, 6 75-82. United States:

Gene expression profiling of Sjogren’s syndrome patients correlation with clinical features.

p16CDKN2A expression during rat tongue carcinogenesis induced by 4-Nitroquinoline-1-oxide. Oral Oncology, 45 640-644. United States,

Characterizing oral cancer progression by free-flow elctrophoresis-based quantitative saliva proteomics.

FOXP3+ T regulatory cells in lesions of oral lichen planus correlated with disease activity. (16): 76-82. United States:

Comparison of gene expression profiles between patients with Sjogren’s syndrome and systemic lupus erythematosus.

Prevalence, severity, and predictors of fatigue in subjects with primary Sjogren's syndrome. Arthritis Rheum, (59): 1780-7. United States:

Proteomic analysis of urine in Sjogren’s syndrome by –TRAQ labeling and mass spectrometry.

Proteomic analysis of cells in whole saliva from oral cancer patients via value-added three-step peptide fractionation and tandem mass spectrometry. J. Molecular and Cell Proteomics, 7 (3): 486-498. United States:

Salivary levels of IL-8 in patients with various oral diseases.

Comparison of human saliva and plasma proteomes. PROTEOMICS - Clinical Applications, (9): 223-229. United States:

Comparison of salivary gland histopathology diagnostic criteria in Sjogren's syndrome.

Salivary dysfunction associated with systemic diseases – systematic review and clinical management recommendations. Oral Surg Oral Med Oral Path Oral Radiol Endo, United States:

Evaluation of activin signaling in squamous cell carcinoma.

Th-1 and Th-2 cytokines in saliva from patients with oral lichen planus. Med. Inflammation, 3 (2): 554-59. United States:

Barriers to accrual in leukoplakia clinical trials.

Salivary cytokines in patients with oral lichen planus before and after treatment with dexamethasone. J Oral Diseases, 12 (1): 112-116. United States:

IL-8 in saliva of patients with various oral diseases.

Detection of apoptotic epithelial cells from brush biopsies and saliva of patients with oral premalignant lesions. Oral Surg Oral Med Oral Path Oral Radiol Endo, United States:

Gene expression profiling of Sjogren’s syndrome patients is distinctly different from Sicca patients.

NFkappaB dependent cytokines in different oral fluids from patients with oral lichen planus. J. Clin. Immunology, 97 (2): 231-237. United States:

A retrospective analysis of oral lesions with epithelial dsyplasia.

Oral health and systemic disease. Minnesota Medical J, 88 (8): 24-28. United States:

Outcomes of oral lesions with epithelial dsyplasia.

Detection of apoptotic epithelial cells from whole saliva of patients with oral preneoplastic lesions and squamous cell carcinoma. Oral Surg Oral Med Oral Path Oral Radiol Endo, 97 (2): 231-237. United States:

Over-expression of interferon-inducible genes is highly correlated with sicca manifestations and autoantibody levels in Sjogren’s syndrome.

CTCAE v3.0 Development of a Comprehensive grading system for the adverse effects of cancer treatment. 13 (3): 176-181. United States:

Salivary cytokines in patients with oral lichen planus treated with dexamethasone.

Myositis ossificans progressive: a case report. Northwest Dentistry, United States:

RNA extraction from brush biopsies of patients with oral leukoplakia.

An Update on the management of dental patients with cardiac arrhythmias. Surg Oral Med Oral Path Oral Radiol Endo, 96 (6): 659-65. United States:

Pro-inflammatory cytokine levels in patients with burning mouth syndrome.

Chewing gum for xerostomia. TUFTS HEALTH and NUTRITON newsletter, 21 (9): 5. United States:

Apoptosis in brush biopsies of patients with oral leukoplakia.

Oral concerns in Lyme disease. Northwest Dentistry, 81 (2): 17-18. United States:

RNA extraction form brush biopsies of patients with oral leukoplakia.

Management of the dental patient with congestive heart failure. J. General Dentistry, 50 (3): 260-269. United States:

Salivary cytokines in patients with oral lichen planus treated with dexamethasone.

Case report of coexisting elderly MESOR-hypertension and circadian amplitude-hypertension (CHAT). Geronto-Geriatrics, (2): 68-86. United States:

IFN-induced genes and Aquaporin-1 are dysregulated in Sjogren’s syndrome patients.

Engineering and governmental challenge: 7-day/24-hour chronobiologic blood pressure and heart rate screening: Part II. Biomedical Instrumentation & Technology, (36): 183-197. United States:

Detection of apoptotic epithelial cells from whole saliva of patients with oral preneoplastic lesions and squamous cell carcinoma.

Update on the diagnosis and treatment of Sjogren’s syndrome and xerostomia. Northwest Dentistry, 78 (4): 24-34. United States:

Differential Gene Expression Patterns Identified in Sjogren's Syndrome Patients Using Microarray Analysis.

TNF-å levels in whole saliva of Sjögren’s syndrome patients before and after oral Human alfa-IFN administration: a pilot study. J. CYTOKINE RESEARCH, United States:

Microarray Analysis to determine Gene Expression Patterns Identified in patients with Sjogren's Syndrome.

Individualized combination chronotherapy of coexisting CHAT and MESOR-hypertension including diltiazem HCl. J. CHRONOBIOLOGY, (23): 455-459. United States:

Quantification of apoptotic epithelial cells from in patients with oral preneoplastic lesions and squamous cell carcinoma.

A clinical evaluation of the local effects of Debacterol versus Kenalog-in-Orabase on recurrent aphthous stomatitis. QUINTESSENCE INTERNATIONAL, 29 (12): 769-775. United States:

Quantification of apoptotic epithelial cells from in patients with oral preneoplastic lesions and squamous cell carcinoma.

The Dental Record. Northwest Dentistry, 76 (5): 11-16. United States:

Estrogen receptors in archived human TMJ tissues.

Dysphagia in patients with Sjogren's syndrome and systemic lupus erythematosus. JOURNAL of ORAL SURGERY, ORAL MEDICINE and ORAL PATHOLOGY, 305-310 United States:

NF kappa_b dependent cytokines in patients with oral squamous cell carcinoma.

Screening dentists for risk factors associated with cardiovascular disease. JOURNAL OF GENERAL DENTISTRY, 42 (10): 440-445. United States:

Oral symptoms in patients with Fibromyalgia.

Dental management of the renal transplant patient. COMPENDIUM OF CONTINUING EDUCATION IN DENTISTRY, 14 (4): 518-532.

Salivary levels of NF kappa_b dependent cytokines in patients with oral squamous cell carcinoma.

Dental management of the heart transplant patient. JOURNAL of GENERAL DENTISTRY, 40 (2): 126-130. United States:

NF kappa_b dependent cytokines in patients with oral lichen planus (OLP).

The effects of Pilocarpine on salivary flow in Sjogren's syndrome patients. JOURNAL of ORAL SURGERY, ORAL MEDICINE and ORAL PATHOLOGY, 71 (11): 545-549. United States:

Analysis of inflammatory cytokines as cancer biomarkers in oral cavity fluids: a preliminary study in human oral premaliganancy model.

The association of xerostomia and inadequate intake in older adults. JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 90 (12): 1688-1693. United States:

NF kappa_B dependent cytokines in patients with oral lichen planus (OLP).

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Emerging Infectious Disease in Dentistry - Part II. Northwest Dentistry, 76 (3): 17-26. United States:

Salivary ctyokine levels in Sjogren’s patients before and after pilocarpine Hcl administration. JOURNAL of DENTAL RESEARCH, United States:

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Chronobiologic vs. conventional blood pressure (BP) monitoring of dental patients. JOURNAL of DENTAL RESEARCH, 74 (5): 1145. United States:

Oral Pilocarpine for post-irradiation xerostomia in patients with head and neck cancer. NEW ENGLAND JOURNAL OF MEDICINE, 329 (6): 390-395. United States:

HIV patient care in the Dental Clinics - Ryan White funding. JOURNAL of DENTAL EDUCATION, 59 (3): 89-90. United States:

Prevalence of oral lesions among individuals with asymptomatic Human Immunodeficiency Virus infection. JOURNAL of GENERAL DENTISTRY, 21 (2): 281-285. United States:

Stimulation of labial salivary flow by Pilocarpine HCl: a pilot study. JOURNAL of ORAL SURGERY, ORAL MEDICINE, ORAL PATH, 80 (4): 424. United States:

Dental management of the liver transplant patient. JOURNAL of ORAL SURGERY, ORAL MEDICINE and ORAL PATHOLOGY, 73 (4): 419-426. United States:

Quantitative assessment of Dysphagia in patients with salivary gland dysfunction. JOURNAL of DENTAL RESEARCH, 74 895. United States:

Dental management of the bone marrow transplant patient. COMPENDIUM OF CONTINUING EDUCATION IN DENTISTRY, 13 (11): 1040-1050. United States:

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Speech problems in patients with Sjogren's syndrome and systemic lupus erythematosus. JOURNAL of DENTAL RESEARCH, 73 460. United States:

Evaluation of an EKG system for the dental office. GENERAL DENTISTRY, 38 (4): 278-281. United States:

Prophylactic antibiotic coverage for dental patients with penile implants. JOURNAL of DENTAL RESEARCH, 71 (460): United States:

Electrocardiographic examination of dental patients with Systemic Lupus Erythematosus. SPECIAL PATIENT CARE in DENTISTRY, 4 (6): 46-51. United States:

A longitudinal correlation of objective and subjective quantitative measurements of xerostomia. JOURNAL of DENTAL RESEARCH, 71 460. United States:

The Periodontal Status of Patients with Sjogren's Syndrome. JOURNAL OF CLINICAL PERIODONTOLOGY, 17 (6): 329-330. United States:

Xerostomia, medications, laboratory values and nutritional status in institutionalized seniors. JOURNAL of DENTAL RESEARCH, 71 460. United States:

Prevalence and significance of Maxillary sinus mucous retention cysts in a general clinic population. JOURNAL of EAR, NOSE and THROAT, 69 (2): 82-91. United States:

Xerostomia, medications, laboratory values and nutritional status in institutionalized seniors. JOURNAL of ORAL SURGERY, ORAL MEDICINE AND ORAL PATHOLOGY, 70 457. United States:

Xerostomia and glossodynia in patients with autoimmune disorders. JOURNAL of EAR, NOSE and THROAT, 68 (4): 791-795. United States:

A comparison of artifical salivas in relieving xerostomia as aseessed by the Mucoprotective relativity index. JOURNAL of DENTAL RESEARCH, 70 1332. United States:

Detection and Management of the patient with Sjogren's Syndrome. COMPENDIUM OF CONTINUING EDUCATION IN DENTISTRY, 8 (8): 578-590. United States:

The effect pilocarpine on salivary flow in patients with Sjogren's syndrome. JOURNAL of DENTAL RESEARCH, 69 1490. United States:

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Salivary flow in HIV patients on clinical trials of Zidovirine (AZT). JOURNAL of DENTAL RESEARCH, 69 1324. United States:

Nalbuphine Hydrochloride: an Effective Analgesic for Patients with a Compromised Respiratory System. COMPENDIUM OF CONTINUING EDUCATION IN DENTISTRY, 9 (8): 458-464. United States:

Progression of oral disease among participant in AZT trials. JOURNAL of DENTAL RESEARCH, 69 1590. United States:

Nutritional Analysis of Older Adults With Sjogren's Syndrome. GERODONTOLOGY, 7 (2): 61-69. United States:

Progression of oral disease among participant in AZT trials. INTERNATIONAL JOURNAL of INFECTIOUS DISEASE, (4): 108. United States:

Zinc Impaired Immunity and Oral Disease in the Geriatric Patient. GERODONTICS, 3 (4): 141-145. United States:

"Educational Value of Emergency Dental Clinics - Faculty Perceptions Versus Reality". JOURNAL of DENTAL EDUCATION, 53 (1): 89-90. United States:

A Systemic, Problem Oriented Approach to the Comprehensive Diagnosis. NORTHWEST DENTISTRY, 67 (3): 11-15. United States:

"EKG Evaluation of SLE Patients". JOURNAL of DENTAL RESEARCH, 68 (3): 296. United States:

Xerostomia: An Increasingly Significant Dental Management Challenge. NORTHWEST DENTISTRY, 66 (3): 14-18. United States:

"Prevalence and Profile of Oral Manifestation in SLE Patients". JOURNAL of DENTAL RESEARCH, 68 (3): 364. United States:

Prostaglandins: Promulgators of Pain. ANESTHESIA PROGRESS, 74 (1): 14-17. United States:

Proteomics reveals lower abundance salivary proteins in Breast Cancer.

Rhodus, N. L. "Naval Hospital Bethesda, MD", Maryland, United States. January 01, 2006.

Selected Grants

Award: Salivary Biomarkers for Sjogren's Syndrome Detection: De
Principal Investigator: Rhodus, Nelson L
Sponsoring Organization: UNIVERSITY OF CALIFORNIA, LOS ANGEL
Award Dates: 2013 - 2014

Award: Salivary Biomarkers for Sjogren's Syndrome Detection: De
Principal Investigator: Rhodus, Nelson L
Sponsoring Organization: UNIVERSITY OF CALIFORNIA, LOS ANGEL
Award Dates: 2013 - 2014

Award: Preliminary Salivary Biomarkers for Sjogren's Detection:
Principal Investigator: Rhodus, Nelson L
Sponsoring Organization: UNIVERSITY OF CALIFORNIA, LOS ANGEL
Award Dates: 2012 - 2013

Award: Salivary Proteomic and Genomic Biomarkers for Primary Sj
Principal Investigator: Rhodus, Nelson L
Sponsoring Organization: UNIVERSITY OF CALIFORNIA, LOS ANGEL
Award Dates: 2007 - 2011

Award: Genomics & Proteomics of Oral Precancer Progression
Principal Investigator: Rhodus, Nelson L
Sponsoring Organization: UNIVERSITY OF CALIFORNIA, LOS ANGEL
Award Dates: 2004 - 2010

Patents
New Investigational Drug.
<b>“A mouthrinse compound to palliate symptoms of oral mucositis as a result of head and neck cancer therapy.” </b>.